p53.html
Quand le nombre de chromosomes déraille 🧬
Mon, 10 Mar 2025 21:00:00 GMT
La mauvaise ségrégation des chromosomes lors de la division cellulaire entraîne des anomalies qui perturbent le ...
The p53 and RB tumour-suppressor pathways
Thu, 08 Nov 2012 07:23:00 GMT
p53 and RB are at the heart of the two main tumour-suppressor pathways that control cellular responses to potentially oncogenic stimuli. Each pathway consists of several upstream regulators and ...
ATM: the p53 booster
Tue, 25 Jun 2024 14:14:00 GMT
The ATM gene (mutated in the disease ataxia telangiectasia) activates the p53 tumor suppressor protein in response to DNA damage, explaining the higher incidence of cancer in AT patients.
Carol Prives
Tue, 08 Oct 2024 13:09:00 GMT
Mutation of the p53 tumor suppressor gene is the most frequent lesion detected in cancer. Consequently, understanding the structure and function of the normal p53 protein and how it differs from the ...
IMSD Community of Scholars (COS) Distinguished Seminar Series
Tue, 04 Mar 2025 23:38:00 GMT
This seminar will focus specifically on the p53 tumor suppressor pathway. The p53 tumor suppressor functions as a transcription factor to activate hundreds of genes. Dr. Lozano’s team has cataloged ...