p53.html
Quand le nombre de chromosomes déraille 🧬
Mon, 10 Mar 2025 21:00:00 GMT
La mauvaise ségrégation des chromosomes lors de la division cellulaire entraîne des anomalies qui perturbent le ...
ATM: the p53 booster
Tue, 25 Jun 2024 14:14:00 GMT
The ATM gene (mutated in the disease ataxia telangiectasia) activates the p53 tumor suppressor protein in response to DNA damage, explaining the higher incidence of cancer in AT patients.
The p53 and RB tumour-suppressor pathways
Thu, 08 Nov 2012 07:23:00 GMT
p53 and RB are at the heart of the two main tumour-suppressor pathways that control cellular responses to potentially oncogenic stimuli. Each pathway consists of several upstream regulators and ...
Unlocking the Potential of PNC-27 Peptide in Cellular and Molecular Research
Thu, 06 Mar 2025 05:25:00 GMT
PNC-27 is a synthetic peptide composed of 32 amino acids. It is engineered to contain the MDM-2 binding domain of the tumor suppressor protein p53 fused with a membrane residency peptide. Its unique ...