p53.html
Scientists aim to repair or replace p53 to combat cancer
Thu, 20 Feb 2025 09:40:58 GMT
Cancer arises when your cells grow uncontrollably and refuse to die when they should. Normally, your body is equipped with regulatory processes to prevent this chaos. One such mechanism involves a ...
ATM: the p53 booster
Tue, 25 Jun 2024 14:14:00 GMT
The ATM gene (mutated in the disease ataxia telangiectasia) activates the p53 tumor suppressor protein in response to DNA damage, explaining the higher incidence of cancer in AT patients.
The p53 and RB tumour-suppressor pathways
Thu, 08 Nov 2012 07:23:00 GMT
p53 and RB are at the heart of the two main tumour-suppressor pathways that control cellular responses to potentially oncogenic stimuli. Each pathway consists of several upstream regulators and ...
PMV Pharmaceuticals to Participate at Upcoming Investor Conferences
Sun, 31 Dec 2000 16:00:00 GMT
PMV Pharmaceuticals, Inc. (Nasdaq: PMVP), a precision oncology company pioneering the discovery and development of small molecule, tumor-agnostic therapies targeting p53, today announced that David H.